The effect of Hypertonic Dextrose injection on the control of pain associated with knee osteoarthritis

Introduction: The purpose of this study was to evaluate the effect of dextrose injection on controlling pain associated with knee osteoarthritis. Methods: To achieve the research objectives, available sampling was done using 80 patients with knee osteoarthritis referring to Taleghani Hospital in 2017 and samples were divided into two groups: 15% dextrose injection and 25% hypertonic dextrose injection. This injection was performed at the beginning of the study, the first week, the fifth week and the ninth week. During these weeks, participants were asked to complete the WOMAC questionnaire implementing the VAS scale. After data collection, independent t-test and two-way variance analysis with repeated measures were used. Findings: The findings showed that 15% and 25% dextrose injection had a significant effect on the visual scale of pain and function of patients, so that, during weekly treatment, scales showed improvement in treatment in these patients. Also, other findings showed that injection of 25% dextrose had a significant visual analog of patient’s pain and function compared to 15%. Conclusion: In general, it can be suggested that the use of dextrose prolotherapy is a simple, safe, inexpensive, accessible and less complicated method than other treatments in these patients.